Regulation of telomerase by telomeric proteins.
By A. Smogorzewska, T. de Lange. Annual Review of Biochemistry, 2004
852 citations recorded by the source corpus.
Subfields: Aging, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/11ad4b81641abe1be88532d14005ada5812c988f
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Aging
In Molecular Biology
- J. Karlseder
- M. Blasco
- Roderick J. O’Sullivan
- Wilhelm Palm
- D. Hockemeyer
- T. de Lange
- G. Hammer
- Kaori Takai
In Physiology
- J. Karlseder
- M. Blasco
- Roderick J. O’Sullivan
- T. de Lange
- Wilhelm Palm
- D. Hockemeyer
- G. Hammer
- Kaori Takai
Citations in the corpus
- How shelterin protects mammalian telomeres. (2008, background): “This equilibrium is due to regulation of telomerase in cis by proteins that bind to the telomeric DNA [reviewed in (175)].”
- NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences (2008, neutral): “NAD may also affect the aging processes through NAD -dependent tankyrases, because tankyrases mediate telomerase activity (270).”
- Telomeres: protecting chromosomes against genome instability (2010, background): “Many of these factors have previously been independently shown to localize to telomeres, where they form a complex to modulate the formation of higher-order telomeric DNA and chromatin, unravel secondary DNA structures and promote resection and strand invasion of the G-overhang into the double-stran”
- Telomere protection by mammalian Pot1 requires interaction with Tpp1 (2007, background): “The interaction of human POT1 with TPP1 has previously been implicated in the regulation of telomere lengt”
- Telomeres and human disease: ageing, cancer and beyond (2005, background): “A number of proteins that bind telomeric repeats, such as the TRF1 and TRF2 complexes mentioned above, regulate telomere length and functio”
- Shelterin: the protein complex that shapes and safeguards human telomeres. (2005, neutral): “These fusions are covalent connections between the C-strand of one telomere and the G-strand of another (Smogorzewska et al. 2002).”