Regulating gene expression through RNA nuclear retention.
By K. Prasanth, S. Prasanth, Zhenyu Xuan, Stephen A Hearn, Susan M. Freier, C. F. Bennett, Michael Ruogu Zhang, David L. Spector. Cell, 2005
691 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/117f2e4a6e4656eff09ad38c6fc20e5f11e1c06b
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In Molecular Biology
- David L. Spector
- John S. Mattick
- J. Wilusz
- Marcel E. Dinger
- Hongjae Sunwoo
- Susan M. Freier
- K. Prasanth
- S. Prasanth
Citations in the corpus
- Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. (2007, background): “Although this mechanism of translational control has only once been documented before (Prasanth et al., 2005), it may prove to be a relatively common form of post-transcriptional gene regulation.”
- FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export (2019, neutral): “Nuclear export of mRNA has been shown to be a critical mechanism regulating gene expression (Prasanth et al., 2005; Wegener and Muller-McNicoll, 2018).”
- The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation (2010, background): “928 Molecular Cell 39, 925–938, September 24, 2010 a2010 Elsevier Independent Sequence Elements in MALAT1 Influence Its Distribution to Nuclear Speckles Posttranscriptional modifications of RNA and/or differential association with specific nuclear-enriched proteins may be responsible for the nuclear”
- A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains (2007, methodology): “Cells were prepared for FISH as previously described [20,21] along with two modified techniques to rigorously preserve cytoplasmic RNA.”
- The SLC3 and SLC7 families of amino acid transporters. (2013, background): “ize to nuclear paraspeckles in C127I mouse mammary tumor cells, suggesting that gene expression might be regulated by nuclear retention (Prasanth et al., 2005).”
- MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. (2009, methodology): “It has previously been shown that RNase A treatment disrupts the integrity of nuclear paraspeckles (Fox et al. 2005; Prasanth et al. 2005), suggesting that one or more RNA species might serve a role in the structure and/or organization of these nuclear bodies.”