Natural Killer Cell Signaling Pathways

By É. Vivier, J. Nunès, F. Vely. Science, 2004

745 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/10bca58c3be0bd404534707d46d214d5f9f8b680

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. M. Colonna
2. Mark Miller
3. G. Lal
4. M. Hernandez
5. L. Piccio
6. M. Cella
7. S. Gilfillan
8. C. Rothlin

Citations in the corpus

• Cutting Edge: TREM-2 Attenuates Macrophage Activation1 (2006, background): “It is possible that DAP12-mediated activation of PI3K may account for the inhibitory effects of TREM-2.”
• Immunobiology of the TAM receptors (2008, background): “1, DX5 and CD69), which recognize ligands on target cell”
• Phospholipase C-γ2 Is a Critical Signaling Mediator for Murine NK Cell Activating Receptors1 (2005, background): “1 signals through FcR , as does Fc RIIIA (34); Ly49D associates exclusively with DAP12 (1, 2), whereas NKG2D uses both DAP10 and DAP12 (14, 15).”
• The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy (2017, background): “During NK cell inhibitory signaling, the phosphatases SHP-1 and SHP-2 dephosphorylate the immunoreceptor tyrosine-based activation motif (ITAM)bearing Vav-1 molecules and prevent the downstream signaling (12, 13) (Figure 2).”