In vitro toxicity of silver nanoparticles at noncytotoxic doses to HepG2 human hepatoma cells.

By K. Kawata, M. Osawa, S. Okabe. Environmental Science and Technology, 2009

683 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Materials Chemistry, Pollution

View Paper: https://www.semanticscholar.org/paper/1098c6928679f2f77b8dd29296bec5a6c31c637e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Health, Toxicology and Mutagenesis

1. Vyom Sharma
2. W. D. De Jong
3. A. Dhawan

In Materials Chemistry

1. Vyom Sharma
2. A. Dhawan
3. Sang Hun Lee
4. Bong-Hyun Jun
5. Anu Kumar
6. Vinod Yadav
7. W. D. De Jong
8. R. Majumdar

In Pollution

1. Vyom Sharma
2. A. Dhawan
3. Tikam Chand Dakal

Citations in the corpus

• A systematic review on silver nanoparticles-induced cytotoxicity: Physicochemical properties and perspectives (2017, neutral): “Polystyrene-coated Ag-NPs caused fewer changes in genetic induction and repression compared to Ag-NPs and AgCO 3 in HepG2 cells [116].”
• The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles. (2011, background): “On the other hand, genotoxicity studies reported that effects on gene mutations and micronucleus formation were at least in part independent of silver ions [17,43].”
• Silver Nanoparticles as Potential Antiviral Agents (2011, background): “Several studies have demonstrated the cytotoxic effects of metal nanoparticles [90,91,92,93], in fact, silver nanoparticles were found to be highly cytotoxic to mammalian cells based on the assessment of mitochondrial function, membrane leakage of lactate dehydrogenase, and abnormal cell morphologie”
• Silver Nanoparticles: Synthesis and Application for Nanomedicine (2019, background): “The intrinsic cytotoxic property of AgNPs has been applied against various types of cancer cells, such as hepatocellular carcinoma [117], lung [118] and breast cancer [119,120], and cervical carcinoma [121].”
• Mechanistic Basis of Antimicrobial Actions of Silver Nanoparticles (2016, background): “Kawata et al. (2009) also reported significant over-expression of three metallothionein genes, MT1H, MT1X, MT2A in human hepatoma cell line (HepG2 cells) after exposure to AgNPs.”