Candida biofilms and their role in infection.

By L. Douglas. Trends in Microbiology, 2003

1,227 citations recorded by the source corpus.

Subfields: Food Science, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/10548f9031c0b96b291295734cd70d04aea3c892

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Food Science

1. J. López-Ribot
2. M. Kaya
3. G. Ramage
4. M. Gulati
5. C. Nobile
6. R. Darouiche
7. K. Konopka
8. E. Kojic

In Infectious Diseases

1. C. Nobile
2. M. Gulati
3. S. Saville
4. J. López-Ribot
5. G. Ramage
6. E. Kojic
7. R. Darouiche
8. K. Konopka

In Molecular Biology

1. S. Saville
2. J. López-Ribot
3. G. Ramage
4. Alexander Johnson
5. Derek P. Thomas
6. M. Kaya
7. M. Gulati
8. C. Nobile

Citations in the corpus

• A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans (2012, background): “See also Figure S4. strain formed a biofilm with typical architecture and thickness (Chandra et al., 2001; Douglas, 2003; Nobile and Mitchell, 2005) of 250 mm in depth, containing both round budding yeast-form cells adjacent to the substrate and hyphal cells extending throughout the biofilm (Figure…”
• Guidelines for the prevention of intravascular catheter-related infections. (2002, neutral): “and Candida species [231] of an extracellular polymeric substance (EPS) consisting mostly of an exopolysaccharide that forms a microbial biofilm layer [218, 232].”
• Candida glabrata, Candida parapsilosis and Candida tropicalis: biology, epidemiology, pathogenicity and antifungal resistance. (2012, background): “Although the mechanisms of biofilm drug resistance are not fully understood, the current consensus is that biofilm tolerance is a complex multifactorial phenomenon involving different molecular mechanisms, restricted penetration of the drug through the matrix and the presence of so-called ‘persister”
• Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient-level quantitative review of randomized trials. (2012, background): “Catheters, like other medical devices, can serve as a substrate for Candida biofilm infection, which exhibits a drug-resistant phenotype [60, 61], necessitating biofilm extirpation for treatment success [62, 63].”
• Extraction and characterization of chitin and chitosan with antimicrobial and antioxidant activities from cosmopolitan Orthoptera species (Insecta) (2015, background): “It can also cause many problems secondary to the use of immuno-suppressive and cytotoxic drugs and powerful antibiotics that suppress the normal microbial flora [60].”
• Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options. (2013, background): “C. albicans biofilms grown in vitro often have a foundation of yeast cells from which a hyphal layer emanates (Douglas, 2003).”
• Guidelines for the prevention of intravascular catheter-related infections. (2011, neutral): “and Candida species [231] of an extracellular polymeric”
• Candida albicans biofilms: development, regulation, and molecular mechanisms (2016, background): “albicans to rapidly proliferate and cause 84 infection [6,9].”
• GENETIC CONTROL OF CANDIDA ALBICANS BIOFILM DEVELOPMENT (2010, neutral): “infections arise as a result of the organisms' ability to grow as a biofilm on implanted medical device”
• Candida Biofilms: an Update (2005, background): “Candida albicans remains the fungal species most commonly associated with biofilm formation (28, 29, 56), and the increase in Candida infections in the last decades has almost paralleled the increase and widespread use of a broad range of medical implant devices, mainly in populations with impaired ”
• Candida Infections of Medical Devices (2004, background): “albicans biofilm is different when it is formed on cellulose filters from when it is formed on catheter disks (7), indicating that it may depend on highly specific contact-induced gene expression (30).”
• Guidelines for the prevention of intravascular catheter-related infections. (2002, neutral): “aureus [229], Pseudomonas aeruginosa [230], and Candida species [231] of an extracellular polymeric substance (EPS) consisting mostly of an exopolysaccharide that forms a microbial biofilm layer [218, 232].”
• Photodynamic Therapy in Dentistry (2007, background): “The ability of C. albicans to form biofilms on epithelial surfaces and prosthetic devices contributes to the failure of antifungal therapy and to recurrent infections (Douglas, 2003).”