Classification and basic pathology of Alzheimer disease

By C. Duyckaerts, Benoit Delatour, Marie-Claude Potier. Acta Neuropathologica, 2009

979 citations recorded by the source corpus.

Subfields: Neurology, Physiology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/104c14d3e596d774b8dfad1eeab72d94930700f0

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Citations in the corpus

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies (2019, neutral): “, 2018a): extracellular deposition of amyloid-β (Aβ) in the form of diffuse and neuritic plaques and the presence of intraneuronal neurofibrillary tangles and neuropil threads within dystrophic neurites consisting of aggregated hyperphosphorylated tau protein (Duyckaerts et al., 2009).”
Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature (2012, background): “Excellent reviews are available about the molecular characteristics of NFTs and A A Ps (27, 28).”
The neuropathological diagnosis of Alzheimer’s disease (2019, background): “In Lewy body dementia, Lewy related pathology affects corticolimbic regions and is often associated with concurrent Alzheimer type pathologic change [120, 121].”
Prion-like transmission of protein aggregates in neurodegenerative diseases (2010, background): “Neurofibrillary tangles and amyloid plaques are the classical neuropathological hallmarks of Alzheimer's diseas”
Myricetin: A Dietary Molecule with Diverse Biological Activities (2016, background): “However, hyperphosphorylation of tau proteins causes entanglement of the helical and straight neurofilaments, thereby contributing to the progression of AD [143].”
Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets (2023, background): “The primary pathological features of AD are extraneuronal amyloid plaques formed by the deposition of Aβ peptide in the brain and intracellular neurofibrillary tangles (NFTs) caused by abnormal aggregation of tau protein.(122) Mechanismly, various factors, including genetics, amyloid protein, tau, A”
Distinct tau prion strains propagate in cells and mice and define different tauopathies (2014, background): “It is noteworthy that AD pathology is characteristically more uniform than other tauopathies (Duyckaerts et al., 2009; Feany et al., 1996), and the tau strains isolated from AD brains were by far the most homogeneous.”
Alzheimer's Disease: Targeting the Cholinergic System (2016, background): “Histopathological analysis reveals, in both humans and animal models of Alzheimer's disease, the presence of amyloid plaques and neurofibrillary tangles in several brain regions, especially in the basal forebrain, frontal lobe [206], hippocampus and cerebral cortex [207-209].”