The CTX-M β-lactamase pandemic

By R. Cantón, Teresa M. Coque. 2006

1,090 citations recorded by the source corpus.

Subfields: Endocrinology, Health, Toxicology and Mutagenesis, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/0fef73636fc0e74fe7064ef04ea88f84114dbb1f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology

1. J. Pitout
2. P. Nordmann
3. Gerard D. Wright
4. M. Gillings
5. Amy Mathers
6. G. Peirano
7. T. Naas
8. H. Stokes

In Health, Toxicology and Mutagenesis

1. Gerard D. Wright

In Molecular Medicine

1. J. Pitout
2. P. Nordmann
3. M. Gillings
4. Gerard D. Wright
5. R. Cantón
6. E. Peterson
7. P. Kaur
8. D. Livermore

Citations in the corpus

• Prevalence and spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae in Europe. (2008, background): “Different features affecting the increase of ESBLs have been discussed previously, particularly for CTX-M enzymes [2].”
• CTX-M Enzymes: Origin and Diffusion (2012, background): “In the United Kingdom, isolation of CTX-M was rare before 2001 and only sporadic cases of CTX-M-9 were described as well as an important outbreak due to CTX-M-26, a variant of CTX-M-25 with three amino acid substitutions (V80A, Q225R, and G242D), which was previously described in Canada (Munday et a”
• The antibiotic resistome: the nexus of chemical and genetic diversity (2007, background): “The extended spectrum β-lactamases of the CTX-M family that are presently a clinical scourg”
• Antimicrobial use in aquaculture re-examined: its relevance to antimicrobial resistance and to animal and human health. (2013, background): “…encountered in the aquatic environment in fish intestines and an opportunistic human pathogen (Tables 2 and 3) (Decousser et al., 2001; Sarria et al., 2001; Humeniuk et al., 2002; Rodriguez et al., 2004; Cantón and Coque, 2006; Navarrete et al., 2008; Rossolini et al., 2008; Cantón et al., 2012).”
• The Role of Epidemic Resistance Plasmids and International High-Risk Clones in the Spread of Multidrug-Resistant Enterobacteriaceae (2015, background): “ESCHERICHIA COLI SEQUENCE TYPE 131 Initial Studies Pertaining to E. coli ST131 Extraintestinal pathogenic E. coli (ExPEC) is an important cause of nosocomial and community infections in humans (especially UTIs, BSIs, and IAIs) (48).”
• Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens. (2011, background): “ISEcp1 elements were first described in the context of the spread of CTX-M family of b-lactamase genes (Karim et al., 2001; Poirel et al., 2003) and numerous examples of linkage of such genes to an ISEcp1 element are now known (Canton & Coque, 2006).”
• Acquired Antibiotic Resistance Genes: An Overview (2011, background): “Furthermore, in the past decade CTX-M enzymes have become very prevalent ESBLs, both in nosocomial and in community settings (Cantón and Coque, 2006).”
• Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer (2016, background): “The potential origin of these genes was identified as the chromosomal DNA of various environmental Kluyvera species, from where they spread very successfully to different bacterial species (Canton and Coque, 2006).”