Experience-dependent and cell-type-specific spine growth in the neocortex

By Anthony Holtmaat, L. Wilbrecht, G. Knott, E. Welker, Karel Svoboda. Nature, 2006

645 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/0d8f3faaf3fd92bd928be8b765096ee3640a901c

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Spine Plasticity in the Motor Cortex (2010, background): “In the barrel cortex, while enriched environment and learning paradigms promote spine formation [37 ,39], experience is also essential for the profound synapse pruning during adolescent development [33].”
Probabilistic brains: knowns and unknowns (2013, background): “A second issue is that the brain does not have the ability to completely rewire itself in a task-dependent manner, as the scaffolding of axons and dendrites is relatively fixed 76 .”
Heterosynaptic structural plasticity on local dendritic segments of hippocampal CA1 neurons (2014, background): “Manipulations leading to experience-dependent plasticity of neuronal circuits also increase the rate of spine shrinkage and elimination (Holtmaat et al., 2006; Tschida and Mooney, 2012; Xu et al., 2009; Yang et al., 2009).”
Learning rules and persistence of dendritic spines (2010, background): “…synaptic transmission, including long-term potentiation (LTP) and long-term depression (LTD) (Lang et al., 2004; Matsuzaki et al., 2004; Okamoto et al., 2004; Otmakhov et al., 2004; Zhou et al., 2004; Segal, 2005; Holtmaat et al., 2006; Kopec et al., 2006; Wang et al., 2007; Yang et al., 2008).”
Training-induced structural changes in the adult human brain. (2008, background): “To date the strongest evidence for learning/traininginduced structural reorganisation in the adult brain comes from primate and non-primate animal studies [27,28,51,53,69,102].”
In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2. (2007, background): “…line described here, the high levels of ChR2-YFP expression in layer 5 pyramidal cells of neocortex present an ideal target population for investigating activity-dependent or developmental cortical plasticity or for behavior-linked circuit mapping (De Paola et al., 2006; Holtmaat et al., 2006).”
Synaptic Mechanisms for Plasticity in Neocortex (2009, background): “Spine formation and retraction are associated with synapse formation and elimination (Trachtenberg et al. 2002, Holtmaat et al. 2006).”