Statistical considerations in the intent-to-treat principle.

By J. Lachin. Controlled Clinical Trials, 2000

644 citations recorded by the source corpus.

Subfields: Economics and Econometrics, Statistics and Probability

View Paper: https://www.semanticscholar.org/paper/0c11cfb0c06b6ccbc3dfaffd235d1f268e511878

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Citations in the corpus

Activated injectable vitamin D and hemodialysis survival: a historical cohort study. (2005, background): “would have grossly misclassified patients’ exposure status (29).”
The impact of school-wide positive behavioral interventions and supports (PBIS) on the organizational health of elementary schools. (2008, methodology): “The present study uses an intent-to-treat approach (Lachin, 2000) to examine the hypothesis that significant changes in the schools’ organizational health would occur after training in school-wide PBIS.”
Ecological Momentary Interventions: Incorporating Mobile Technology Into Psychosocial and Health Behavior Treatments (2009, methodology): “Intent-to-treat analyses include all randomized participants in the group to which they were assigned (regardless of treatment or follow-up adherence), thus providing a more conservative estimate of treatment effects (Lachin, 2000).”
Reflection as a strategy to enhance task performance after feedback (2009, methodology): “, excluding those who did not participate in a minimum amount of the intervention) to examine the effect of the experimental treatment (also referred to as ‘‘per protocol analysis”, ‘‘explanatory analysis”, or ‘‘analysis by treatment received”) (Lachin, 2000).”
Enhancing treatment outcome of patients at risk of treatment failure: meta-analytic and mega-analytic review of a psychotherapy quality assurance system. (2010, methodology): “The statistical methods used in the previous feedback studies reflect two distinct approaches: effectiveness analysis based on the intent-totreat (ITT) principle and efficacy analysis (Atkins, 2009; Lachin, 2000).”
Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. (2002, methodology): “Comparison of the 2 interventions was principally by intention to treat, although the relationship of outcomes to adherence to treatment was also examined via an efficacy subset analysis.(35) The Fisher exact test and survival analysis were used to carry out the comparison in terms of transition to ”
Chapter 8: Assessing risk of bias in included studies (2008, background): “Here, the most recently observed outcome measure is assumed to hold for all subsequent outcome assessment times (Lachin 2000, Unnebrink 2001).”
The benefits of self-compassion and optimism exercises for individuals vulnerable to depression (2010, methodology): “Imputation methods (intent-to-treat analyses) have been widely used in controlled clinical trials to address issues with high attrition rates and missing data (Lachin, 2000).”
Intervention for First Graders With Limited Number Knowledge (2015, background): “The ITT approach makes no assumptions about student participation after the offer to participate; it is an estimate based on those offered services (Lachin, 2000) after consent from parents was received.”
Controlled-Release Phentermine/Topiramate in Severely Obese Adults: A Randomized Controlled Trial (EQUIP) (2011, methodology): “Analysis C was an ITT analysis as defined by Lachin (23) that included all randomized patients.”
CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. (2012, background): “Thus, many trials accruing few participants and reporting large treatment effects may have been stopped earlier than planned but failed to report this action.”