Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks

By Daniel Zilberman, Devin Coleman-Derr, Tracy J. Ballinger, Steven Henikoff. Nature, 2008

602 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/0b7ea3a7875421c50be1f0253860454599bd0679

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Peter A. Jones
2. S. Baylin
3. G. Liang
4. Daniel D. De Carvalho
5. F. Lay
6. Xiaojing Yang
7. P. Voigt
8. Wee-Wei Tee

In Plant Science

1. Peter A. Jones
2. Michel Caboche
3. D. Reinberg

Citations in the corpus

• Epigenetic Determinants of Cancer. (2016, background): “Z is present in the nucleosomes flanking the start sites, and its presence is strongly anticorrelated with DNA methylation (Zilberman et al. 2008; Yang et al. 2012).”
• Rethinking how DNA Methylation Patterns are Maintained (2009, background): “Z, which is preferentially located at the start sites of genes, is counter-distributed with the distribution of DNA methylatio”
• Epigenetic regulation of gene responsiveness in Arabidopsis (2014, background): “Z occupation in gene bodies in Arabidopsis (Zilberman et al., 2008).”
• H2A.Z-containing nucleosomes mediate the thermosensory response in Arabidopsis. (2010, unknown): “Microscopy Cell 140, 136–147, January 8, 2010 ª2010 Elsevier Inc. 139 140 Cell 140, 136–147, January 8, 2010 ª2010 Elsevier Inc. of HTA11:GFP reveals incorporation into euchromatin as in other studies (Figures S2A and S2B) (Zilberman et al., 2008).”
• Site-specific biotinylation of purified proteins using BirA (2015, background): “BLRP (Biotin ligase recognition peptide) contains a core of AviTag and is 23 residues: (MAGGLNDIFEAQKIEWHEDTGGS) (5,49).”
• Linking DNA methylation and histone modification: patterns and paradigms (2009, background): “and, in plants, excludes the histone variant H2AZ from nucleosome”
• Gene Body Methylation can alter Gene Expression and is a Therapeutic Target in Cancer (2014, background): “Both of thesemarks are considered antagonistic to DNA methylation, which might explain why they were refractory to rebound methylation (Gal-Yam et al., 2008; Kondo et al., 2008; Zilberman et al., 2008).”
• Integrative epigenomic mapping defines four main chromatin states in Arabidopsis (2011, background): “Z, which is preferentially deposited near the 50-end of genes and promotes transcriptional competence, antagonizes DNA methylation and vice versa (Zilberman et al, 2008).”