A pathway for mitotic chromosome formation

By J. Gibcus, K. Samejima, Anton Goloborodko, Itaru Samejima, N. Naumova, J. Nuebler, Masato T. Kanemaki, Linfeng Xie, J. R. Paulson, W. Earnshaw and 2 more. Science, 2018

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Chromatin organization by an interplay of loop extrusion and compartmental segregation (2017, background): “A more realistic picture would start from mitotic chromosomes (55), where neither compartments nor TADs are observed (20, 62), which we leave for future investigations.”
HiGlass: web-based visual exploration and analysis of genome interaction maps (2017, background): “Despite the large amounts of generated Hi-C data, major challenges remain in (i) identifying known features unambiguously [14]; (ii) discovering new features; (iii) establishing relationships between Hi-C features and known (epi)genetic profiles; (iv) establishing the effects of various genetic, bio”
Real-time imaging of DNA loop extrusion by condensin (2018, neutral): “2 kbp/s) (17) or a bacterial SMC complex (0.”