HiGlass: web-based visual exploration and analysis of genome interaction maps

By Peter Kerpedjiev, Nezar Abdennur, Fritz Lekschas, C. McCallum, K. Dinkla, Hendrik Strobelt, Jacob M. Luber, Scott Ouellette, A. Azhir, Nikhil Kumar and 7 more. Genome Biology, 2017

1,864 citations recorded by the source corpus.

We present HiGlass, an open source visualization tool built on web technologies that provides a rich interface for rapid, multiplex, and multiscale navigation of 2D genomic maps alongside 1D genomic tracks, allowing users to combine various data types, synchronize multiple visualization modalities, and share fully customizable views with others. We demonstrate its utility in exploring different experimental conditions, comparing the results of analyses, and creating interactive snapshots to share with collaborators and the broader public. HiGlass is accessible online at http://higlass.io and is also available as a containerized application that can be run on any platform.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/2cca729822ebcf8fee3b14d6416bc796614eb1c9

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In Molecular Biology

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2. Ming Hu
3. Ross C. Hardison
4. Yanli Wang
5. Yun Li

Citations in the corpus

• Automated assembly scaffolding using RagTag elevates a new tomato system for high-throughput genome editing (2022, neutral): “Cooler and HiGlass were used to visualize Hi-C heatmaps [53, 54].”
• The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions (2017, background): “Users can also explore Hi-C data in Juicebox [16] and Hi-Glass [17] with great speed, but currently, neither of them provide other types of chromatin interaction data, such as Capture Hi-C or ChIA-PET.”