Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress
By D. Allan Butterfield, C. Lauderback. 2002
911 citations recorded by the source corpus.
Subfields: Pharmacology, Physiology
View Paper: https://www.semanticscholar.org/paper/0aa377a39f18fea10755a48ce5a3dfed382e720c
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In Pharmacology
In Physiology
Citations in the corpus
- Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review (2007, background): “…of biomolecules including proteins, amino acids, unsaturated lipids and DNA, and ultimately produce molecular alterations related to aging, arteriosclerosis and cancer (Gardner, 1997), Alzheimer's disease (Butterfield and Lauderback, 2002), Parkinson's disease, diabetes and asthma (Zarkovic, 2003).”
- Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71 (2002, background): “In Alzheimer’s disease (AD), where reactive substances have been implicated in the progression of this agerelated neurodegenerative disease, protein carbonyl levels, considered a detectable marker of protein oxidation, are increased in several regions of the brain (Markesbery 1997; Butterfield and K”
- Amyloid β-peptide (1-42)-induced Oxidative Stress and Neurotoxicity: Implications for Neurodegeneration in Alzheimer's Disease Brain. A Review (2002, background): “[1, 2 ]). Further, based mostly on genetic grounds, the 42-amino acid peptide, amyloid b-peptide (1 – 42) [Ab(1 – 42), Fig. 1], may be central to the pathogenesis of the disease.[3] Our laboratory”
- Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. (2002, background): “Further, the AD brain is under extensive oxidative stress indexed by protein oxidation, lipid peroxidation, DNA and RNA oxidation, advanced glycation endproducts, protein nitration, mitochondrial abnormalities, reactive oxygen species (ROS) formation, and other markers (reviewed in [13,14,58] ).”
- Pesticides and oxidative stress: a review. (2004, background): “For example, there is extensive evidence for oxidative stress as an important mechanism of neurodegeneration in Alzheimer’s Disease [1,2].”