Direct protein interaction underlies gene-for-gene specificity and coevolution of the flax resistance genes and flax rust avirulence genes.

By P. Dodds, G. Lawrence, A. Catanzariti, T. Teh, C. Wang, M. Ayliffe, Bostjan Kobe, J. Ellis. Proceedings of the National Academy of Sciences of the United States of America, 2006

798 citations recorded by the source corpus.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/0a4691d7d27e44feefdbc93407d67d189769787c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Plant Science

Citations in the corpus

The Arabidopsis NPR1 protein is a receptor for the plant defense hormone salicylic acid. (2012, background): “The straightforward logic is that NB-LRRs recognize Avr proteins via direct protein-protein interaction, which has been observed in the case of the flax R protein L6 (Dodds et al., 2006).”
Plant NBS-LRR proteins in pathogen sensing and host defense (2006, background): “Those interactions recapitulate the in vivo specificity of the L isoforms, supporting the hypothesis that this interaction drives pathogen detection in plant”
Defended to the Nines: 25 Years of Resistance Gene Cloning Identifies Nine Mechanisms for R Protein Function[OPEN] (2018, background): “The AvrL567 effector from the fungal pathogen Melampsora lini is another effector that directly interacts with its cognate receptor, theflaxL5,L6, andL7NLRs,whichareencodedbyallelic genes (Dodds et al., 2004, 2006).”
Nutrient uptake in rust fungi: how sweet is parasitic life? (2011, background): “Papers from Australian researchers working with the pathosystem Melampsora lini/Linum usitatissimum indicate that there are a number of haustorium-specific secreted proteins that interact directly with corresponding host resistance gene products (Catanzariti et al. 2006; Dodds et al. 2004, 2006).”
Fungal effector proteins. (2009, background): “Indeed, in a survey involving just six flax rust strains, twelve AvrL567 sequence variants (known as AvrL567A to AvrL567L) were identified, six of which (A, B, D, F, J, and L) were avirulent variants that triggered HR in flax lines carrying the L5, L6, or L7 genes, and five (C, G, H, I, and K) were ”
Elicitors, effectors, and R genes: the new paradigm and a lifetime supply of questions. (2007, methodology): “Dodds, Ellis, Lawrence, and colleagues have put together a very important body of work on this topic, working with the flax/flax-rust pathosystem that was also used by Flor (47, 48, 53, 54, 57).”
Role of phytohormones in insect-specific plant reactions (2012, background): “Although the PTI/ETI model is sometimes regarded as an oversimplification [3], the molecular identification of the involved ligands and receptors has enabled conclusions to be drawn about the specificity of recognition in plant–pathogen interactions: in general, PTI is based on non-specific recognit”
A Novel Role for the TIR Domain in Association with Pathogen-Derived Elicitors (2007, background): “This is supported by a recent report of direct L–AvrL interactions in yeast [14].”