Heritable gene targeting in zebrafish using customized TALENs

By Peng Huang, A. Xiao, Mingguo Zhou, Zuoyan Zhu, Shuo Lin, Bo Zhang. Nature Biotechnology, 2011

701 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/0868fc6d47a7f91b8d4f56b711014233b46dc468

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In Molecular Biology

Citations in the corpus

Genome Engineering of Crops with Designer Nucleases (2012, background): “, 2011), zebrai sh (Huang et al., 2011; Sander et al., 2011a), rats (Tesson et al.”
PINK1 is degraded through the N-end rule pathway (2013, background): “Furthermore, PINK1(1-155)-YFP, a mutant with an N-end stabilizing residue was stably localized in the cytosol (Fig.”
FLASH Assembly of TALENs Enables High-Throughput Genome Editing (2012, positive): “19 15–22 The TALENs used in these studies were constructed on different architectures and composed of variable numbers of TALE repeats making it difficult to ascertain whether these parameters affect the efficiencies of nuclease activity.”
Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing? (2019, positive): “Genome editing using targetable nucleases such as ZFNs (Bibikova et al., 2002; Doyon et al., 2008; Geurts et al., 2009; Urnov et al., 2010), TALENs (Huang et al., 2011; Tesson et al., 2011; Joung and Sander, 2013) and CRISPR/Cas9 (Cong et al., 2013; Jinek et al., 2013; Mali et al., 2013a; Hwang et a”
TALENs: a widely applicable technology for targeted genome editing (2012, positive): “10, 28 More recently, a repeat with hypervariable residues NH has been reported to be more specific than the NN repeat, but with only slightly lower activity.”
Discovery and resupply of pharmacologically active plant-derived natural products: A review (2015, methodology): “The applicability of these species as disease models has been additionally expanded by recent implementation of the techniques of gene editing in both nematodes (Wood et al., 2011) and zebrafish (Huang et al., 2011), allowing for rapid and low-cost genetic engineering.”
Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair (2014, methodology): “While sequencespecific TALE nucleases can be readily assembled from TALE repeats specific to each nucleotide (Cermak et al. 2011; Huang et al. 2011; Sander et al. 2011), sgRNAs for the CRISPR/Cas9 system can be easily generated by cloning of target-specific oligonucleotides into sgRNA expression vec”