Scaffolds for tissue fabrication

By P. Ma. 2004

1,012 citations recorded by the source corpus.

Abstract Tissue engineering is an interdisciplinary and multidisciplinary field. It has shown great promise in generating living alternatives for harvested tissues and organs for transplantation and reconstructive surgery. Materials and fabrication technologies are critically important for tissue engineering in designing temporary, artificial extracellular matrices (scaffolds), which support three-dimensional tissue formation. This review briefly introduces the concept of tissue engineering, and illustrates the relationship between tissue engineering and materials science and engineering. Important scaffold design principles are described. The most frequently used materials and fabrication technologies for scaffolds are reviewed. Some exciting new developments in scaffold materials and fabrication technologies are also discussed.

Subfields: Biomaterials, Biomedical Engineering

View Paper: https://www.semanticscholar.org/paper/0812fc79f9f0a175f9d241e112f431335d278dc1

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In Biomaterials

In Biomedical Engineering

Citations in the corpus

A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds (2021, background): “Advanced technologies are now available to fabricate biomaterials (natural/synthetic) in designing scaffolds which support the formation of complex 3D tissues, many of them with functional vascular networks that match their in vivo counterparts [12,13].”
Hyaluronic acid based scaffolds for tissue engineering--a review. (2013, methodology): “Other rapid prototyping techniques such as fused deposition modelling (FDM) and stereolithography are also being explored for scaffold fabrication (Ma, 2004).”
Application of conductive polymers, scaffolds and electrical stimulation for nerve tissue engineering (2011, background): “Polymeric nanofibres can be processed by a number of techniques, such as drawing, template synthesis, phase separation, self-assembly and electrospinning (Ashammakhi et al., 2008; Smith and Ma, 2004).”
Is It Time to Start Transitioning From 2D to 3D Cell Culture? (2020, methodology): “The solvent is then removed via evaporation and the salt particles are leached out leaving behind a porous structure (Liu and Ma, 2004).”
Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size (2013, neutral): “14,36,37 Using this FIG.”
Cell Responses to Surface and Architecture of Tissue Engineering Scaffolds (2011, methodology): “The gas adsorption method is relevant to the study of porosity in nano-featured and nanomodified scaffolds (Ma, 2004), and is based on the electrical forces of attraction that bind”
POLYMERIC SCAFFOLDS IN TISSUE ENGINEERING APPLICATION: A REVIEW (2011, background): “PLA, PGA, and PLGA copolymers are among the most commonly used synthetic polymers in tissue engineering [29].”
Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/polyamide composite scaffolds for bone tissue engineering. (2007, background): “Phase inversion is based on the principle that a homogeneous multicomponent system, under certain conditions, becomes thermodynamically unstable and tends to separate into more than one phase in order to lower the system free energy [4].”
A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering. (2012, background): “Researchers will strive to fulfil those afore mentioned objectives through the utilization of isolated cells [8e11], tissue inducing substances [12e14] and/or scaffolds [3,4,6,15].”
Bioceramics of calcium orthophosphates. (2010, background): “The major function of scaffolds is similar to that of the natural ECM that assists proliferation, differentiation and biosynthesis of cells.”