Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease.

By A. Fasano, T. Not, Wenle Wang, S. Uzzau, I. Berti, A. Tommasini, S. Goldblum. The Lancet, 2000

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Human Intestinal Barrier Function in Health and Disease (2016, background): “about sixfold increased in the intestinal submucosa of patients with active celiac disease compared with healthy controls.(123)”
Intestinal permeability – a new target for disease prevention and therapy (2014, background): “Other diseases such as celiac disease need to be mentioned as an example of a disease related to intestinal permeability [175,176].”
Impact of Omega-3 Fatty Acids on the Gut Microbiota (2017, background): “Zonulin, a detectable protein in human serum [63], has been shown to reflect intestinal permeability [64,65].”
Intestinal barrier function: molecular regulation and disease pathogenesis. (2009, background): “in patients with active celiac disease.(194) Furthermore, antagonism of zonulin prevented gliadin-induced permeability changes in intestinal biopsy specimens from patients with celiac disease.”