Cellular immune correlates of protection against symptomatic pandemic influenza

By S. Sridhar, S. Begom, A. Bermingham, K. Hoschler, W. Adamson, W. Carman, T. Bean, W. Barclay, J. Deeks, A. Lalvani. Nature Medicine, 2013

857 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology

View Paper: https://www.semanticscholar.org/paper/0751cec70343f7d5d393d5304e4ea77eb1689aef

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Barney S. Graham
2. F. Krammer
3. M. Kanekiyo

In Immunology

1. Bjoern Peters
2. Alessandro Sette
3. Morten Nielsen
4. J. Greenbaum
5. H. Ljunggren
6. Shane Crotty
7. F. Krammer
8. Massimo Andreatta

Citations in the corpus

• Next-Generation Influenza Vaccines. (2020, background): “Although there is indirect evidence that CD8 T cells directed to conserved epitopes confer some protection in humans (McMichael et al. 1983; Sridhar et al. 2013;Wang et al. 2015) and there is ample evidence for protection in animalmodels, significant efficacy against influenza diseasemay depend on t”
• Adaptive immunity to SARS-CoV-2 and COVID-19 (2021, positive): “Cross-reactive T cells can provide some degree of protective immunity against respiratory viral infections, as seen in the influenza H1N1 2009 pandemic (Sridhar et al., 2013; Wilkinson et al., 2012).”
• Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection (2021, background): “In the context of influenza, CD8 TEMRA cells were associated with protection against severe disease in humans (55).”
• Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19 (2020, positive): “It is also tempting to speculate that such responses may provide at least partial protection against SARS-CoV-2, given that pre-existing T cell immunity has been associated with beneficial outcomes after challenge with the pandemic influenza virus strain H1N1 (Sridhar et al., 2013; Wilkinson et al.,”
• Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals (2020, positive): “The presence of cross-reactive T cells was found to correlate with less severe disease (Sridhar et al., 2013; Wilkinson et al., 2012).”