Lipid A modification systems in gram-negative bacteria.

By C. Raetz, C. M. Reynolds, M. Trent, R. Bishop. Annual Review of Biochemistry, 2007

1,279 citations recorded by the source corpus.

Subfields: Ecology, Food Science, Genetics

View Paper: https://www.semanticscholar.org/paper/05e4248544109d62232b8eecd7e2b624883eab19

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Citations in the corpus

Antimicrobial Actions and Applications of Chitosan (2021, background): “For example, gram-negative bacteria present a more negative charge than gram-positive bacteria because LPS is often attached to phosphorylated groups [128,129].”
Mechanistic diversity in ATP-binding cassette (ABC) transporters (2016, background): “Bacterial ABC exporters have diverse roles, including the extrusion of (often lipid-linked) building blocks required for cell wall assembly 5-7 .”
A comparison of the endotoxin biosynthesis and protein oxidation pathways in the biogenesis of the outer membrane of Escherichia coli and Neisseria meningitidis (2012, positive): “Modifications of E. coli LPS and role in pathogenesis Periplasmic modifications to E. coli LPS basic structure can play an important role in adaptation and pathogenesis of the microorganism (Trent et al., 2006; Raetz et al., 2007).”
Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production (2010, background): “The lpxA gene is essential for the biosynthesis of lipid A and therefore LPS (26).”
The Kennedy pathway—De novo synthesis of phosphatidylethanolamine and phosphatidylcholine (2010, background): “In bacteria, PE is a precursor for macromolecules such as LPS and periplasmic membranederived oligosaccharide (12, 24).”
Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems (2008, background): “Several excellent reviews describe the biosynthesis pathway in detail (39, 119, 390, 391).”
Bacterial membrane lipids: diversity in structures and pathways. (2016, background): “For permissions, please e-mail: journals.permissions@oup.com 133 of the outer membrane is formed by lipid A, the lipophilic anchor of lipopolysaccharide (LPS) (Raetz and Dowhan 1990; Raetz et al. 2007).”
Lipopolysaccharide modification in Gram-negative bacteria during chronic infection. (2016, methodology): “Diverse covalent modifications of lipid A may occur during its transit from the periplasmic side of the inner membrane to the outer leaflet of the outer membrane (Raetz et al. , 2007), which are important for niche adaptation and can influence the virulence of the pathogen (Needham & Trent, 2013).”
Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria (2014, positive): “…has been described to negatively regulate eptB , which mediates the modiﬁcation of the outer Kdo (3-deoxy-D-manno -octulosonic acid) residues of LPSs with PEtN ( Figure 1 ) (Reynolds et al., 2005; Raetz et al., 2007). eptB is indirectly inﬂuenced by the PhoP/PhoQ system (Moon and Gottesman, 2009).”