Antimicrobial Actions and Applications of Chitosan

By Cai-Ling Ke, Fu-Sheng Deng, C-Y. Chuang, Ching-Hsuan Lin. Polymers, 2021

755 citations recorded by the source corpus.

Chitosan is a naturally originating product that can be applied in many areas due to its biocompatibility, biodegradability, and nontoxic properties. The broad-spectrum antimicrobial activity of chitosan offers great commercial potential for this product. Nevertheless, the antimicrobial activity of chitosan varies, because this activity is associated with its physicochemical characteristics and depends on the type of microorganism. In this review article, the fundamental properties, modes of antimicrobial action, and antimicrobial effects-related factors of chitosan are discussed. We further summarize how microorganisms genetically respond to chitosan. Finally, applications of chitosan-based biomaterials, such as nanoparticles and films, in combination with current clinical antibiotics or antifungal drugs, are also addressed.

Subfields: Biomaterials, Food Science, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/1eef6cdafb5aed0cf2e8ca44b1cd29c3b8bc6e5f

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In Biomaterials

1. M. Civera
2. N. Acosta
3. C. Arias
4. A. Alcántara
5. I. Aranaz
6. B. Elorza
7. Angeles Heras Caballero

Citations in the corpus

• Chitosan: An Overview of Its Properties and Applications (2021, background): “It has also been hypothesized that chitosan can penetrate the cells and block RNA transcription as a result of adsorption with bacterial DNA [9].”