Switching on and off fear by distinct neuronal circuits

944 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear (2010, positive): “In addition, different types of neurons in the basal amygdala signal fear memory or extinction, which may shift the balance between the context-dependent expression of fear and/or extinction after conditioning (157).”
Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress (2012, background): “Indeed, unit recording data suggests that BLA neurons processes extinction via reciprocal connectivity with prefrontal and hippocampal areas (Herry et al 2008, Herry et al 2010),. BLA input is responsible for conditioned fear signaling in PL (Laviolette et al 2005, Sotres-Bayon et al 2010)…”
Amygdala inhibitory circuits and the control of fear memory. (2009, background): “In the BA, extinction training is associated with a rapid switch in the balance of CS-evoked activity between two distinct populations of projection neurons (Herry et al., 2008).”
Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear (2010, neutral): “…(BLA), a storage site for fear memories, is thought to mediate the initial acquisition of extinction (Herry et al., 2006; Sotres-Bayon et al., 2007; Herry et al., 2008) and the expression of extinction memory via inhibition of central amygdala (CeA) output neurons (Quirk et al., 2003; Likhtik et…”