Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity.

By Kathleen D. Metzler, T. Fuchs, W. Nauseef, D. Reumaux, J. Roesler, I. Schulze, V. Wahn, V. Papayannopoulos, Arturo Zychlinsky. Blood, 2011

749 citations recorded by the source corpus.

Subfields: Immunology, Infectious Diseases, Physiology

View Paper: https://www.semanticscholar.org/paper/0582d30385b02b2b1cf8a2447040fa0b4baf9642

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. P. Kubes
2. Arturo Zychlinsky
3. N. Borregaard
4. V. Brinkmann
5. B. McDonald
6. A. Mócsai
7. V. Papayannopoulos
8. C. Rosales

In Infectious Diseases

1. P. Kubes
2. V. Brinkmann

In Physiology

1. V. Brinkmann
2. P. Kubes
3. Arturo Zychlinsky

Citations in the corpus

• Neutrophil extracellular traps: Is immunity the second function of chromatin? (2012, methodology): “, 2011) is an objective and quantitative method (Papayannopoulos et al., 2010; Metzler et al., 2011) to measure NET formation.”
• Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis. (2013, positive): “NE is abundantly expressed within NETs and is involved in their formation (41, 45, 47, 53).”
• Neutrophils, from marrow to microbes. (2010, background): “CGD neutrophils and MPO-deficient neutrophils, therefore, do not form NETs (Bianchi et al., 2009; Metzler et al., 2010).”
• A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis (2014, neutral): “Neutrophils from these patients fail to form NETs when stimulated with physiological NET stimuli such as fungi or the ROS agonist phorbol myristate acetate (PMA) (Fuchs et al., 2007; Metzler et al., 2011).”