Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health.

By Michael Joseph Meaney, M. Szyf, J. Seckl. Trends in Molecular Medicine, 2007

702 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Obstetrics and Gynecology, Pediatrics, Perinatology and Child Health

View Paper: https://www.semanticscholar.org/paper/0465ea29ac0223d00badb78564f7ac9cb01c3825

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In Behavioral Neuroscience

In Obstetrics and Gynecology

In Pediatrics, Perinatology and Child Health

Citations in the corpus

How experience gets under the skin to create gradients in developmental health. (2010, neutral): “Meaney MJ, Szyf M, Seckl JR. 2007.”
Intergenerational Trauma: Convergence of Multiple Processes among First Nations peoples in Canada (2009, positive): “…prenatal environment (reflected by maternal under-nutrition and birth weight of pups) was associated with increased risk of metabolic disorders and cardiovascular illness in the offspring, and that epigenetic factors might have been responsible for such outcomes (Meaney, Szyf & Seckl, 2007).”
Sex-Specific Programming of Offspring Emotionality after Stress Early in Pregnancy (2008, background): “Although recent emphasis has been placed on the involvement of epigenetic machinery in the programming of early life events, the influence of fetal antecedents on the epigenome remains unknown (Meaney et al., 2007).”
The Integration of Genetic Propensities into Social-Control Models of Delinquency and Violence among Male Youths (2008, background): “A particularly interesting case is the interplay between the maternal behavior of mother rats and the glucorticoid receptor gene for offspring’s responses to stress (Meaney, Szyf, and Seckl 2007).”
Brain-gut interactions in inflammatory bowel disease. (2013, background): “Deficient maternal care in rats increases glucocorticoid receptor promoter methylation leading to decreased expression in the hippocampus, a recognized target for glucocorticoid feedback (77).”
Epigenetics and the biological definition of gene x environment interactions. (2010, background): “Thus, it is possible that environmentally driven changes in neuronal transcriptional signals could potentially remodel the methylation state of specific regions of the DNA (Meaney & Szyf, 2005).”
Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (2010, background): “Although we focus here on epigenetic inheritance systems, it is important to note that parental information can also be passed to offspring via social or cultural inheritance systems (Avital and Jablonka, 2000; Champagne and Meaney, 2001; Jablonka and Lamb, 1995; Meaney et al., 2007; Weaver et al., ”