Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm.

By X. Ye, S. Al‐Babili, A. Klöti, Jing Zhang, P. Lucca, P. Beyer, I. Potrykus. Science, 2000

2,286 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/045ff1346799e361b6e69dd918fc4142e0175522

How researchers see this paper

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In Genetics

1. Sudhir Kumar
2. Steven M. L. Smith
3. Alan J. Filipski
4. Jiayang Li
5. M. Ashraf
6. George L. Graef
7. Margarida M. Oliveira
8. Q. Qian

In Molecular Biology

1. H. Sharma
2. M. M. Chaves
3. P. Jauhar
4. Jaume Flexas
5. H. Medrano
6. Sudhir Kumar
7. M. Ashraf
8. Alan J. Filipski

Citations in the corpus

• A comparison between crop domestication, classical plant breeding, and genetic engineering (2002, background): “The example of high provitasical breeding should be subject to more stringent regu- min A “golden rice” comes to mind (Ye et al., 2000). lation, similar to that used for GE cultivars.”
• Breeding high-yield superior quality hybrid super rice by rational design (2016, positive): “[INSERT FIG 5 HERE] Where appropriate, transgenic approaches will be used, such as for insecticidal Cry proteins or for grain biofortification with provitamin A [99, 100], iron and zinc”
• Vitamin synthesis in plants: tocopherols and carotenoids. (2006, background): “PSY from daffodil and the bacterial phytoene desaturase (crtI) from Erwinia uredorva were targeted for expression in rice endosperm (149).”
• Seed coats: Structure, development, composition, and biotechnology (2005, background): “In theory, any protein could be expressed in the seed, as could non-protein materials such as vitamin A precursors in rice (Xudong et al., 2000) if the metabolic pathways in the developing seed were modified.”
• Genetically modified food in perspective: an inquiry‐based curriculum to help middle school students make sense of tradeoffs (2004, background): “Genetic engineering of food has been touted as a way of growing enough food for an increasing world population, and improving the nutrient intake of populations at risk for deficiencies — as in the case of Golden Rice, which contains a precursor to vitamin A (Ye et al. 2000).”
• Functional foods development: Trends and technologies (2011, background): “Golden Rice is an effective source of vitamin A. American Journal of Clinical Nutrition, 89, 1776-1783.”