Sequential use of mushroom body neuron subsets during drosophila odor memory processing.

By M. Krashes, A. Keene, Benjamin Leung, J. Armstrong, S. Waddell. 2007

423 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Genetics, Immunology

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Citations in the corpus

Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, background): “…molecular and circuit mechanisms, anesthesia resistant memory and anesthesia sensitive memory, contribute to memory at this retention time (Dudai et al., 1976; Folkers et al., 1993; Isabel et al., 2004; Krashes and Waddell, 2008; Aso et al., 2010; Pitman et al., 2011; Knapek et al., 2011).”
The neuronal architecture of the mushroom body provides a logic for associative learning (2014, background): “As different functions of learning and memory, such as acquisition and retrieval, have been attributed to different KC classes (Isabel et al., 2004; Krashes et al., 2007), MBONs integrating across lobes may function in coordinating different phases of learning and memory.”
Parallel Pathways for Cross-Modal Memory Retrieval in Drosophila (2013, methodology): “These results are supported by previous studies in both larval and adult flies (Krashes et al., 2007; Honjo and FurukuboTokunaga, 2009; Pauls et al., 2010).”
A neural circuit mechanism integrating motivational state with memory expression in Drosophila (2009, background): “Synaptic output from the MB a0b0 neurons is required to consolidate appetitive memory whereas output from the ab subset is specifically required for memory retrieval (Krashes et al., 2007; Krashes and Waddell, 2008).”
A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster (2015, background): “DPMs contain 5HT and GABA, but not ACh or dopamine The shared requirement for activity during memory consolidation (Krashes et al., 2007; Krashes and Waddell, 2008) as well as the extensive physical connectivity as determined by membrane-localized GRASP (Pitman et al., 2011) strongly suggests that…”
System-like consolidation of olfactory memories in Drosophila (2013, background): “2A), which is consistent with other studies (Krashes et al., 2007).”
Three Dopamine Pathways Induce Aversive Odor Memories with Different Stability (2012, background): “Considering the selective phenotype of MB-M3 neurons and differential functions of the lobe systems [25,30,31,32,33], it is likely that electric shock induces qualitatively different memory traces in parallel.”
Synaptic organization in the adult Drosophila mushroom body calyx (2009, methodology): “Random distribution of presynaptic labeling was estimated by rotating either the nc82 or the synaptotagmin channel by 90° relative to the actin-GFP channel (Lang et al., 2007).”
Short Neuropeptide F Acts as a Functional Neuromodulator for Olfactory Memory in Kenyon Cells of Drosophila Mushroom Bodies (2013, methodology): “Data were evaluated using the software Prism (GraphPad) as previously de- scribed (Kremer et al., 2010) using Kolmogorov–Smirnov and Bartlett’s test, followed by one-way ANOVA or Kruskal–Wallis test.”
A pair of inhibitory neurons are required to sustain labile memory in the Drosophila mushroom body (2011, positive): “These data led us to propose that reverberant activity in a recurrent MB a0b0-to-DPM neuron circuit is required to hold labile memory and for consolidation to LTM within ab neurons [5, 9, 23, 24], where output is critical for retrieval of LTM [9, 23, 24].”
Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body (2007, background): “, (iii) that MTM is acquired in mushroom body α/β neurons and persists there via recurrent activity involving the mushroom body α′/β′ DPM (dorsal-paired medial) neurons and the mushroom body α/β neurons themselve”
Transposition Driven Genomic Heterogeneity in the Drosophila Brain: A Dissertation (2012, positive): “Current understanding suggests the γ neurons play a role in short- term memory (Blum et al., 2009; Trannoy et al., 2011) whereas the α’β’ neurons are required to drive memory consolidation (Krashes et al., 2007; Krashes and Waddell, 2008).”
Cell Type-Specific Transcriptome Analysis in the Drosophila Mushroom Body Reveals Memory-Related Changes in Gene Expression (2016, neutral): “…these data point to KCs being important for STM, / KCs playing a role in memory consolidation, and / KCs being important for LTM (Blum et al., 2009; Krashes et al., 2007; Tomchik and Davis, 2009; Trannoy et al., 2011; Yu et al., 2006) – although there are exceptions to this general picture (Aso et…”