Resources and Biological Activities of Natural Polyphenols
By An-Na Li, Sha Li, Yu-Jie Zhang, Xiangrong Xu, Yu-ming Chen, Huabin Li. Nutrients, 2014
821 citations recorded by the source corpus.
The oxidative stress imposed by reactive oxygen species (ROS) plays an important role in many chronic and degenerative diseases. As an important category of phytochemicals, phenolic compounds universally exist in plants, and have been considered to have high antioxidant ability and free radical scavenging capacity, with the mechanism of inhibiting the enzymes responsible for ROS production and reducing highly oxidized ROS. Therefore, phenolic compounds have attracted increasing attention as potential agents for preventing and treating many oxidative stress-related diseases, such as cardiovascular diseases, cancer, ageing, diabetes mellitus and neurodegenerative diseases. This review summarizes current knowledge of natural polyphenols, including resource, bioactivities, bioavailability and potential toxicity.
Subfields: Biochemistry, Endocrinology, Diabetes and Metabolism, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/0207644ca2af4c0e8707d4ca8ce539a638720342
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In Biochemistry
In Endocrinology, Diabetes and Metabolism
In Organic Chemistry
Citations in the corpus
- Polyphenols: Extraction Methods, Antioxidative Action, Bioavailability and Anticarcinogenic Effects (2016, background): “The main sources of polyphenols are fruits such as berries, grapes, citrus fruits, apricots, apples, plums, cherries, peaches and tropical fruits [4,65].”
- The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility (2016, background): “Polyphenols are also implicated in preventing chronic diseases such as cardiovascular diseases, diabetes, obesity, and neurodegenerative diseases, among others [2–5].”
- The Role of Oxidative Stress and Antioxidants in Liver Diseases (2015, background): “When the ROS is excessive, the homeostasis will be disturbed, resulting in oxidative stress, which plays a critical role in liver diseases and other chronic and degenerative disorders [9].”