Predicting protein function from sequence and structural data.

By James D. Watson, Roman A. Laskowski, Janet M. Thornton. Current Opinion in Structural Biology, 2005

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COFACTOR: an accurate comparative algorithm for structure-based protein function annotation (2012, background): “Accordingly, many contemporary approaches have been designed to identify local structural similarity of functionally important residues for drawing functional inferences (7,8).”
Improving structure-based function prediction using molecular dynamics (2009, methodology): “Some methods also combine information from sequence and structure (Friedberg, 2004; Watson et al., 2005).”
Protein structure prediction on the Web: a case study using the Phyre server (2009, background): “The practical applications of protein structure prediction are many and varied, including guiding the development of functional hypotheses about hypothetical protein”
FragBag, an accurate representation of protein structure, retrieves structural neighbors from the entire PDB quickly and accurately (2010, background): “Indeed, many methods for protein function (1, 2) and structure (3) prediction rely on finding such neighbors.”
Predicting protein function from sequence and structure (2007, unknown): “However, as the volume of data has increased, so too have the number and sophistication of computational methods for predicting functio”