William C. Comb
Molecular Biology · 2015
A researcher in the Science corpus: 2 papers; trusts 1 researcher and is trusted by 0 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 44 citations into it
Whom William C. Comb trusts
Their strongest outbound trust, strongest first, inferred from their citations.
- David M. Sabatini (in Molecular Biology)
Papers from William C. Comb's perspective
Ordered by how strongly the researchers William C. Comb trusts endorse each paper. Same corpus, a different order for every researcher.
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1 (Science)
- mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the Vacuolar H+-ATPase (Science)
- Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress (Molecules and Cells)
- Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome (Cell)
- Amino acid signalling upstream of mTOR (Nature reviews. Molecular cell biology)
- TSC2 mediates cellular energy response to control cell growth and survival. (Cell)
- Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. (Molecules and Cells)
- TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling (Nature Cell Biology)
- AMPK phosphorylation of raptor mediates a metabolic checkpoint. (Molecules and Cells)
- Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. (Genes & Development)
Their papers
- The amino acid transporter SLC38A9 is a key component of a lysosomal membrane complex that signals arginine sufficiency to mTORC1 (2015) — 763 citations
- Nutrient Sensing Mechanisms and Pathways (2015) — 1,040 citations