Paul V. Fish
Molecular Biology · 2012–2023
A researcher in the Science corpus: 8 papers; trusts 1 researcher and is trusted by 0 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 156 citations into it
Whom Paul V. Fish trusts
Their strongest outbound trust, strongest first, inferred from their citations.
- Christof Niehrs (in Molecular Biology)
Papers from Paul V. Fish's perspective
Ordered by how strongly the researchers Paul V. Fish trusts endorse each paper. Same corpus, a different order for every researcher.
- Structural Basis of Wnt Recognition by Frizzled
- Secreted and transmembrane wnt inhibitors and activators. (Cold Spring Harbor Perspectives in Biology)
- The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing.
- Epigenetic Modifications as Therapeutic Targets (Nature Biotechnology)
- Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
- Strategies for Tuning the Selectivity of Chemical Probes that Target Serine Hydrolases
- Pd-Catalyzed Intramolecular Aminoalkylation of Unactivated Alkenes: Access to Diverse N-Heterocycles.
- Irreversible inhibitors of serine, cysteine, and threonine proteases.
- Esterase activities in the blood, liver and intestine of several preclinical species and humans.
- Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit
Their papers
- Epigenetic protein families: a new frontier for drug discovery (2012) — 1,283 citations
- Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity (2023) — 7 citations
- Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit (2022) — 13 citations
- Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling (2021) — 46 citations
- Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity. (2021) — 11 citations
- Structural Insights into Notum Covalent Inhibition (2021) — 14 citations
- Small-molecule inhibitors of carboxylesterase Notum (2021) — 25 citations
- NOTUM from Apc-mutant cells biases clonal competition to initiate cancer (2021) — 203 citations