NOTUM from Apc-mutant cells biases clonal competition to initiate cancer

By D. Flanagan, Nalle Pentinmikko, Kalle Luopajärvi, N. Willis, K. Gilroy, A. Raven, L. Mcgarry, J. Englund, Anna T. Webb, S. Scharaw and 26 more. 2021

203 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Oncology

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In Molecular Biology

1. Paul V. Fish

Citations in the corpus

• Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity (2023, background): “Recent studies have shown there is a growing understanding of the role Notum plays in human disease such as osteoporosis [4,5] and colorectal cancer [6,7].”