J. Kelly

Molecular Biology · Science · 2001–2013

A researcher in the Science corpus: 14 papers; trusts 4 researchers and is trusted by 6 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 105 citations into it; #8,089 of 17,773 by trust here, #3,333 by citations
• Physiology — 41 citations into it; #1,592 of 2,276 by trust here, #671 by citations

Whom J. Kelly trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. Douglas M. Fowler

Who trusts J. Kelly overall

1. Douglas M. Fowler
2. Richard I. Morimoto
3. F. Hartl

Papers from J. Kelly's perspective

Ordered by how strongly the researchers J. Kelly trusts endorse each paper. Same corpus, a different order for every researcher.

1. Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations.
2. Protein stability promotes evolvability.
3. Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein
4. Darwinian Evolution Can Follow Only Very Few Mutational Paths to Fitter Proteins
5. Protein 3D Structure Computed from Evolutionary Sequence Variation
6. Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details.
7. High Resolution Mapping of Protein Sequence–Function Relationships
8. Deep mutational scanning: assessing protein function on a massive scale
9. Nucleated conformational conversion and the replication of conformational information by a prion determinant. (Science)
10. Therapeutic approaches to protein-misfolding diseases (Nature)

Their papers

• A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function (2012) — 245 citations
• Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade (2012) — 702 citations
• Adapting Proteostasis for Disease Intervention (2008) — 2,402 citations
• Functional amyloid--from bacteria to humans. (2007) — 1,029 citations
• Functional Amyloid Formation within Mammalian Tissue (2005) — 807 citations
• Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. (2006) — 622 citations
• Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition (2003) — 768 citations
• Protein Native State Stabilization by Placing Aromatic Side Chains in N-Glycosylated Reverse Turns (2011) — 163 citations
• Repurposing Diflunisal for Familial Amyloid Polyneuropathy: A Randomized Clinical Trial (2013) — 667 citations
• Biological and chemical approaches to diseases of proteostasis deficiency. (2009) — 1,170 citations
• Opposing Activities Protect Against Age-Onset Proteotoxicity (2006) — 896 citations
• ARGONAUTE4 Control of Locus-Specific siRNA Accumulation and DNA and Histone Methylation (2003) — 84 citations
• Therapeutic approaches to protein-misfolding diseases (2003) — 810 citations
• The folding mechanism of a -sheet: the WW domain1 (2001) — 274 citations