Jan H. M. Schellens
Molecular Biology · 2000–2019
A researcher in the Science corpus: 10 papers; trusts 1 researcher and is trusted by 0 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 36 citations into it
- Genetics — 11 citations into it
Whom Jan H. M. Schellens trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Papers from Jan H. M. Schellens's perspective
Ordered by how strongly the researchers Jan H. M. Schellens trusts endorse each paper. Same corpus, a different order for every researcher.
- Potent antibody therapeutics by design (Nature reviews. Immunology)
- Antibody pharmacokinetics and pharmacodynamics. (Journal of Pharmacy and Science)
- Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. (New England Journal of Medicine)
- Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. (New England Journal of Medicine)
- Ovarian cancer: strategies for overcoming resistance to chemotherapy (Nature Reviews. Cancer)
- Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. (Journal of the National Cancer Institute)
- Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors (EMBO Molecular Medicine)
- A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. (Journal of Clinical Oncology)
- Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan. (Journal of the National Cancer Institute)
- Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR (Nature)
Their papers
- Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. (2009) — 3,580 citations
- Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan. (2000) — 682 citations
- Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. (2010) — 991 citations
- Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer. (2019) — 1,107 citations
- Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600-Mutant Anaplastic Thyroid Cancer. (2018) — 745 citations
- Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM (2011) — 333 citations
- Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies (2010) — 690 citations
- A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent (2004) — 704 citations
- Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C. (2002) — 741 citations
- Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. (2001) — 1,185 citations