M. Eck

Molecular Biology · 2001–2016

A researcher in the Science corpus: 12 papers; trusts 2 researchers and is trusted by 7 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 48 citations into it; #13,276 of 17,773 by trust here, #2,333 by citations
• Materials Chemistry — 8 citations into it
• Computational Theory and Mathematics — 5 citations into it

Whom M. Eck trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. Tony Pawson

Who trusts M. Eck overall

1. R. Dominguez
2. K. Holmes

Papers from M. Eck's perspective

Ordered by how strongly the researchers M. Eck trusts endorse each paper. Same corpus, a different order for every researcher.

1. Improved methods for building protein models in electron density maps and the location of errors in these models.
2. The conformational plasticity of protein kinases. (Cell)
3. Gefitinib-Sensitizing EGFR Mutations in Lung Cancer Activate Anti-Apoptotic Pathways (Science)
4. Refinement of macromolecular structures by the maximum-likelihood method.
5. Untangling the ErbB signalling network (Nature reviews. Molecular cell biology)
6. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy (Science)
7. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. (New England Journal of Medicine)
8. Assembly of Cell Regulatory Systems Through Protein Interaction Domains (Science)
9. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. (Cancer Cell)
10. Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers (International Journal of Cancer)

Their papers

• EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. (2005) — 4,065 citations
• Structure and regulation of Src family kinases (2004) — 687 citations
• Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. (2007) — 1,098 citations
• The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP (2008) — 2,013 citations
• Novel mutant-selective EGFR kinase inhibitors against EGFR T790M (2009) — 979 citations
• A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors (2011) — 620 citations
• Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2 (2003) — 206 citations
• Overcoming EGFR T790M and C797S resistance with mutant-selective allosteric inhibitors (2016) — 757 citations
• Mechanism and function of formins in the control of actin assembly. (2007) — 842 citations
• Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. (2005) — 3,130 citations
• EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy (2004) — 9,841 citations
• Structure of a human Tcf4–β-catenin complex (2001) — 135 citations