Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche

By Y. Bi, D. Ehirchiou, T. Kilts, C. Inkson, M. Embree, W. Sonoyama, Li Li, A. Leet, B. Seo, Li Zhang and 2 more. Nature Medicine, 2007

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Biologics for tendon repair (2014, background): “The existence of TSPC was further confirmed in subsequent studies with human, equine, rabbit, rat and mouse tendons [28–35].”
Mesenchymal Stem Cells Derived from Dental Tissues vs. Those from Other Sources: Their Biology and Role in Regenerative Medicine (2009, positive): “The successful isolation and characterization of PDLSCs have led to the identification of tendon MSCs by the same approaches (Bi et al., 2007).”
The regulation of tendon stem cell differentiation by the alignment of nanofibers. (2010, methodology): “5 10(4) cells/cm2, n 1⁄4 3) subcutaneously into the dorsal surface of 8–10-week-old female immunocompromised athymic nude mice (Harlan, n 1⁄4 3) [12].”
Extracellular matrix: a dynamic niche component during cancer progression (2012, neutral): “…of the ECM receptor integrins or reduction of ECM components, includ ing the glycoproteins osteopontin (Kollet et al., 2006; Lymperi et al., 2010), tenascin C (Garcion et al., 2004), or biglycan (Bi et al., 2007), reduces the number of stem cells in different vertebrate and invertebrate systems.”
Extracellular Matrix Degradation and Remodeling in Development and Disease (2011, background): “Likewise, both tenascin C and biglycan are critical stem cell niche components of the subventricular zone and tendon systems, respectively (Garcion et al. 2004; Bi et al. 2007).”