Faculty Opinions recommendation of Mitosis. Microtubule detyrosination guides chromosomes during mitosis.
By Claire E. Walczak. 2015
51 citations recorded by the source corpus.
Subfields: Cell Biology
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Citations in the corpus
- UniProt: the universal protein knowledgebase (2016, background): “(17) performed experiments in human cells and information about detyrosination is reportedin all human tubulin-alpha isotypes that contain a tyrosine residue at the C-terminus (UniProtKB Q71U36, P68363, Q9BQE3, Q13748 and Q6PEY2).”
- The tubulin code: a navigation system for chromosomes during mitosis (2016, background): “RNAi-mediated knockdown of TTL forces spindle microtubule detyrosination, including astral microtubules and, consequently, polar chromosomes move in all directions, including towards the cell cortex, in a CENP-E-dependent manner [29] (Figure 3E).”