Mutation rates in mammalian genomes

By Sudhir Kumar, Sankar Subramanian. Proceedings of the National Academy of Sciences of the United States of America, 2002

599 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/fe215666781d58346ac5311e2f77903bcbc2aa6a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Sudhir Kumar
2. Koichiro Tamura
3. Masatoshi Nei
4. S. Blair Hedges
5. Jianzhi Zhang
6. Xionglei He
7. Glen Stecher
8. David Haussler

In Molecular Biology

1. Sudhir Kumar
2. David Haussler
3. Koichiro Tamura
4. W. James Kent
5. Masatoshi Nei
6. Adam C. Siepel
7. S. Blair Hedges
8. Xionglei He

In Plant Science

1. David Haussler
2. Koichiro Tamura
3. Sudhir Kumar
4. Masatoshi Nei
5. Adam C. Siepel
6. Xionglei He
7. W. James Kent
8. Jianzhi Zhang

Citations in the corpus

• Temporal patterns of fruit fly (Drosophila) evolution revealed by mutation clocks. (2003, methodology): “…of Life Sciences, Arizona State University; Department of Biological Sciences, Tokyo Metropolitan University, Tokyo, Japan Drosophila melanogaster has been a canonical model organism to study genetics, development, behavior, physiology, evolution, and population genetics for nearly a century.”
• Rapid Subfunctionalization Accompanied by Prolonged and Substantial Neofunctionalization in Duplicate Gene Evolution (2005, methodology): “To examine how t increases over time since duplication, we again used dS between duplicates as a proxy for time [dS 1 in mammals corresponds to 250 MY after duplication (Kumar and Subramanian 2002)].”
• Repair and genetic consequences of endogenous DNA base damage in mammalian cells. (2004, background): “The mammalian genome would be expected to present a larger target for mutagenesis, and the similarity of mutation rates among lineages with vastly different generation times points to a major contribution of replicationindependent processes to overall mutation rate in mammalian genomes (77).”
• Comparative analyses of multi-species sequences from targeted genomic regions (2003, result): “but in contrast to studies defending the molecular cloc”
• Evolvability (2006, unknown): “We note that estimates of actual mutation rates in various organisms are available [Drake et al. 1998; Kimura 1968; Kumar and Subramanian 2002].”
• The origin and evolution of model organisms (2002, background): “However, accounting for base composition differences among lineage”
• MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment (2004, background): “45,46 MEGA contains the disparity index test 46 for this purpose.”