Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map

By S. Wicks, Raymond T. Yeh, W. Gish, R. Waterston, Ronald H. A. Plasterk. Nature Genetics, 2001

732 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

WormBase: a multi-species resource for nematode biology and genomics (2004, background): “WormBase also contains extensive information from largescale genomics analyses, including precomputed sequence similarity searches, protein motif analyses, results from systematic RNAi screens (10±12), single nucleotide polymorphisms (SNPs) (13,14), microarray expression studies (15) and the assignm”
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span (2004, result): “Indeed, PTEN-null cells are sensitive to inhibition of TOR by a rapamycin derivative (CCI-779) (Neshat et al., 2001; Podsypanina et al., 2001), which is currently in phase II clinical trials as an anticancer agent (Huang and Houghton, 2003).”
An initial map of insertion and deletion (INDEL) variation in the human genome. (2006, background): “For example, studies of genetic variation in Drosophila melanogaster and Caenorhabditis elegans have shown that INDELs represent between 16% and 25% of all genetic polymorphisms in these species (Berger et al. 2001; Wicks et al. 2001).”