The role of mutations in epigenetic regulators in myeloid malignancies

By A. Shih, O. Abdel-Wahab, Jay P. Patel, R. Levine. Nature Reviews. Cancer, 2012

733 citations recorded by the source corpus.

Subfields: Genetics, Hematology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/fd323d3f25f5fb8eb323d452402ada1c58918fcd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. K. Helin
2. Olivier Elemento
3. Howard Y. Chang
4. Anshul B Kundaje
5. Michael Snyder
6. Luciano Di Croce

In Hematology

1. R. Majeti

In Molecular Biology

1. Jason D. Buenrostro
2. W.J. Greenleaf
3. Howard Y. Chang
4. Beijing Wu
5. M. Corces
6. Anshul B Kundaje
7. R. Majeti
8. Luciano Di Croce

Citations in the corpus

• Transcriptional regulation by Polycomb group proteins (2013, background): “; and from the Novo Nordisk Foundation, the Danish Cancer Society and the Danish Council for Strategic Research (12-110503) to K.”
• EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation (2013, background): “In this way, EZH2 mutation appears analogous to many of the somatic mutations in acute myeloid leukemia (AML), which induce a myeloproliferative phenotype when expressed in murine hematopoietic stem cells but, when expressed together, cooperate to form AML (Shih et al., 2012).”
• Lineage-specific and single cell chromatin accessibility charts human hematopoiesis and leukemia evolution (2016, background): “PAX5 expression in acute leukemias: higher B-lineage specificity than CD79a and selective association with t(8;21)-acute myelogenous leukemia.”