Recognition of single-stranded RNA viruses by Toll-like receptor 7.

By Jennifer M. Lund, L. Alexopoulou, A. Sato, M. Karow, N. Adams, N. Gale, A. Iwasaki, R. Flavell. Proceedings of the National Academy of Sciences of the United States of America, 2004

1,990 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology

View Paper: https://www.semanticscholar.org/paper/fcbaebe0cc9678eef988114b0d180601f935d43d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. R. Medzhitov
2. R. Flavell
3. A. Iwasaki
4. A. García‐Sastre
5. Zhijian J. Chen
6. F. Weber
7. S. Ghosh
8. B. Beutler

In Immunology

1. Shizuo Akira
2. Zhijian J. Chen
3. R. Medzhitov
4. S. Ghosh
5. Taro Kawai
6. Daniel B. Stetson
7. M. Hayden
8. R. Randall

Citations in the corpus

• Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses (2006, background): “In addition, ssRNAs of FLUAV and VSV are capable of triggering IFN induction via TLR7 (13, 38 ), and the FLUAV NS1 protein also binds to viral ssRNA (22).”
• Type I interferons in host defense. (2006, positive): “TLR7 and TLR8 detect single-stranded RNA (ssRNA) and viruses that contain ssRNA genomes (Diebold et al., 2004; Heil et al., 2004; Lund et al., 2004).”