Immature frontal lobe contributions to cognitive control in children: evidence from fMRI.

By Silvia A. Bunge, Nicole M. Dudukovic, Moriah E. Thomason, Chandan J. Vaidya, John D. E. Gabrieli. Neuron, 2002

1,350 citations recorded by the source corpus.

Event-related fMRI was employed to characterize differences in brain activation between children ages 8-12 and adults related to two forms of cognitive control: interference suppression and response inhibition. Children were more susceptible to interference and less able to inhibit inappropriate responses than were adults. Effective interference suppression in children was associated with prefrontal activation in the opposite hemisphere relative to adults. In contrast, effective response inhibition in children was associated with activation of posterior, but not prefrontal, regions activated by adults. Children failed to activate a region in right ventrolateral prefrontal cortex that was recruited for both types of cognitive control by adults. Thus, children exhibited immature prefrontal activation that varied according to the type of cognitive control required.

Subfields: Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/fca3634e0a592b38b9955a87a1e68bf3e318db89

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In Cognitive Neuroscience

Citations in the corpus

Attention and inhibition in bilingual children: evidence from the dimensional change card sort task. (2004, background): “Bunge et al. (2002) concluded that immature prefrontal activation accounted for poor performance on inhibition tasks; development brings both improved performance and a shift in the brain areas associated with these functions.”
The effects of poor quality sleep on brain function and risk taking in adolescence (2013, neutral): “Whereas reward sensitivity shows curvilinear developmental patterns, peaking in mid adolescence , impulse control gradually increases throughout adolescence, showing linear improvements into adulthood (Bunge et al., 2002; Galván et al., 2006; Geier et al., 2010).”
Activation of Right Inferior Frontal Gyrus during Response Inhibition across Response Modalities (2007, methodology): “…studies using the manual go/no-go task (Buchsbaum et al., 2005; Nakata et al., 2005; Rubia et al., 2005; Matsubara et al., 2004; Aron et al., 2003; Bunge et al., 2002; Durston et al., 2002; Braver et al., 2001; Liddle et al., 2001; Menon et al., 2001; Rubia et al., 2001; Sakagami et al., 2001; de…”
Executive Functions (2012, neutral): “Yet evidence indicates that diverse types of inhibitory control of attention and action appear to share substantially similar neural bases (Bunge et al. 2002, Cohen et al. 2012).”
Dissociable Contributions of Prefrontal and Parietal Cortices to Response Selection (2002, neutral): “Parietal activation has been observed previously for incongruent relative to congruent or neutral flanker trials (e.g., Carter et al., 2000; Casey et al., 2000; Bunge et al., 2002).”