Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects
By N. Skakkebaek, E. R. Meyts, K. Main. Human Reproduction, 2001
2,336 citations recorded by the source corpus.
Subfields: Molecular Biology, Surgery, Urology
View Paper: https://www.semanticscholar.org/paper/fbe5a4f4e9b90d664593d5acd30b53f89726b608
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In Molecular Biology
Citations in the corpus
- Endocrine-disrupting chemicals: an Endocrine Society scientific statement. (2009, background): “In the male (Table 2), cryptorchidism, hypospadias, oligospermia, and testicular cancer have been proposed to be linked as the testicular dysgenesis syndrome (TDS) arising from disturbed prenatal testicular development (14, 21).”
- Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes (2015, neutral): “The testicular dysgenesis syndrome (TDS) hypothesis posits an interrelationship among these adverse outcomes, as manifestations of altered prenatal testicular development in humans (Aschim et al. 2004; Bay et al. 2006; Biggs et al. 2002; Kaleva and Toppari 2005; Scott et al. 2007; Sharpe and Skakkeb”
- Endocrine Disrupting Chemicals and Disease Susceptibility (2011, background): “[85] have suggested that the incidences of cryptorchidism, hypospadias and poor semen quality are risk factors for one another and that they are all predictive of developing testicular germ cell cancers.”
- Effect of Endocrine Disruptor Pesticides: A Review (2011, background): “Recently, a relation has been reported between cryptorchidism and persistent pesticide concentration in maternal breast milk [47,62,63].”
- Assessing exposure to phthalates - the human biomonitoring approach. (2011, background): “This so-called human testicular dysgenesis syndrome in many ways resembles the phthalate syndrome in rats [38–44].”
- The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration. (2003, background): “This concept may explain the nonfortuitous association of disorders in the testicular dysgenesis syndrome described in the male (258) and the polyendocrine-metabolic syndrome in the female (146).”
- Components of plastic: experimental studies in animals and relevance for human health (2009, background): “Accordingly, less severe manifestations would result in impaired spermatogenesis while other symptoms such as testicular cancer may be present in more severely affected individuals (Skakkebaek et al. 2001).”
- EAU guidelines on male infertility. (2002, background): “This testicular dysgenesis syndrome (TDS) can result in maldescent, reduced fertility and an increased risk for malignant development [30].”