Maturation of mouse NK cells is a 4-stage developmental program.
By L. Chiossone, Julie Chaix, Nicolas Fuséri, C. Roth, É. Vivier, T. Walzer. Blood, 2009
788 citations recorded by the source corpus.
Subfields: Immunology, Oncology
View Paper: https://www.semanticscholar.org/paper/7b3e9a29031c558dc39a2624e4a30ddc8e3cb151
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In Immunology
- Chao Yang
- T. Walzer
- M. Smyth
- Joseph C. Sun
- Monica S. Thakar
- Alex M. Abel
- S. Malarkannan
- Levi J. Rupp
In Oncology
Citations in the corpus
- Natural Killer Cells: Development, Maturation, and Clinical Utilization (2018, background): “NK cells begin expressing neither receptor, known as the double-negative population, and progress to CD27+CD11b− (Stages B, C, and D), double-positive (DP, Stages E), and the CD27−CD11b+ (Stage F) NK cells, which are considered the most mature (33, 37).”
- The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation (2012, background): “1 NKp46) NK cells that can undergo further phenotypic maturation and express the integrins CD49b (DX5) and CD11b (Chiossone et al., 2009; Kim et al., 2002; Walzer et al., 2007).”
- TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway (2016, background): “Moreover, splenic NK cells in both mouse strains had similar phenotypes, with a predominance of immature CD27+CD11b− NK cells (Fig.”