Microbial production of vitamin B12

By Martens Jh, H. Barg, M. Warren, D. Jahn. Applied Microbiology and Biotechnology, 2002

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Vitamin B12 excretion by cultures of the marine cyanobacteria Crocosphaera and Synechococcus (2010, background): “…for most marine eukaryotic phytoplankton (Provasoli and Carlucci 1974; Droop 2007) that is required for the activity of several vital enzymes in central metabolism (e.g., methylmalonyl-CoA mutase, methionine synthase, and type II ribonucleotide reductase; Raux et al. 2000; Martens et al. 2002).”
Molecular genetic approaches to increasing mineral availability and vitamin content of cereals (2007, background): “If untreated, deficiencies in vitamin B12 result in the fatal condition of pernicious anemia and partial deficiencies have been correlated with a range of neurological symptoms (Martens et al., 2002).”
Overview of Mercury Methylation Capacities among Anaerobic Bacteria Including Representatives of the Sulphate-Reducers: Implications for Environmental Studies (2009, background): “In addition to Clostridium species, mercury methylation has been reported for different methylcobalamin-producing facultative aerobic bacteria (Martens et al. 2002) such as Streptococcus spp.”
Screening of a natural biodiversity of lactic and propionic acid bacteria for folate and vitamin B12 production in supplemented whey permeate (2010, background): “0 was reviewed as being critical for reaching high vitamin B12 yields (Martens et al., 2002).”