Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo.
By M. Nieuwdorp, T. V. van Haeften, M. Gouverneur, H. Mooij, Miriam H P van Lieshout, M. Levi, J. Meijers, F. Holleman, J. Hoekstra, H. Vink and 2 more. Diabetes, 2006
607 citations recorded by the source corpus.
Subfields: Critical Care and Intensive Care Medicine, Epidemiology, Neurology
View Paper: https://www.semanticscholar.org/paper/fa9d66cac16f5d7f10d19fe2cdaf93008ac8d1ed
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In Epidemiology
Citations in the corpus
- Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies (2021, background): “Insulin impacts the endothelium (Rask-Madsen et al., 2001; Arcaro et al., 2002; Rask-Madsen et al., 2010), and insulin treatment is intimately involved with the phenomenon of insulin resistance, which is a risk factor for atherosclerosis (Nigro et al., 2006).”
- Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. (2013, background): “This coincides with endothelial dysfunction and a general systemic increased vascular permeability in humans (Nieuwdorp et al., 2006).”
- The endothelial glycocalyx: composition, functions, and visualization (2007, background): “Recently, it was shown that the systemic glycocalyx volume of healthy volunteers, as assessed by comparing the intravascular distribution volume of a glycocalyx-permeable and a glycocalyximpermeable tracer, was halved within 6 h after induction of acute hyperglycemia [76].”
- Inflammation and coagulation (2010, background): “It was shown recently that specific disruption of the glycocalyx results in thrombin generation and platelet adhesion within a few minutes (114, 115).”