Unraveling V(D)J Recombination: Insights into Gene Regulation

By David H. Jung, F. Alt. 2004

386 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f9705b90f814a9c3c54b5e1ebc93a8e4971ca2a2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. David H. Jung
2. R. Mostoslavsky
3. Cosmas C. Giallourakis
4. F. Alt

In Molecular Biology

1. R. Mostoslavsky
2. David H. Jung
3. F. Alt

Citations in the corpus

• The evolution of adaptive immune systems. (2006, neutral): “The RAG1/RAG2 proteins were later shown to recognize the recombination signal sequences flanking the V(D)J gene segments to initiate the double-stranded DNA breaks and recruitment of other proteins required for their recombination (Oettinger et al., 1990; Jung and Alt, 2004).”
• Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus. (2006, background): “Variable regions of antigen receptors, including IgH and IgL chains and TCR chains, are assembled from germline V, D, and J gene segments through a site-specific recombination reaction known as V(D)J recombination (2, 3).”