The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling
By Michael Loran Dustin, J. Cooper. Nature Immunology, 2000
757 citations recorded by the source corpus.
Subfields: Cell Biology, Immunology, Oncology
View Paper: https://www.semanticscholar.org/paper/f9252bc1670c12021ddc8e0e038c9360644fa89d
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In Cell Biology
In Immunology
- C. McGlade
- V. Barr
- S. Bunnell
- T. Yamazaki
- David I. Hong
- Julia R. Kardon
- Q. Sattentau
- Michael Loran Dustin
In Oncology
Citations in the corpus
- The Immunological Synapse (2014, result): “A plausible model based on this similarity has been proposed and initial results support some aspects of the model [29].”
- T cell receptor ligation induces the formation of dynamically regulated signaling assemblies (2002, background): “the transmembrane proteins that define the immunological synapse (TCR, CD4, CD28, LFA-1, CD43, CD45) (Monks et al., 1998; Grakoui et al., 1999; Dustin and Cooper, 2000; Johnson et al., 2000; Krummel et al., 2000; Allenspach et al., 2001; Delon et al., 2001; Lee et al., 2002; Zal et al., 2002).”
- Adhesion of membranes via receptor-ligand complexes: Domain formation, binding cooperativity, and active processes (2009, background): “The membrane separation is comparable to the length of the receptor-ligand complexes, which have a typical extension between 15 and 40 nanometers [17].”
- HIV-1 Cell to Cell Transfer across an Env-induced, Actin-dependent Synapse (2004, background): “Recruitment of receptors and adhesion molecules into the immunological synapse is an actin-driven process (30).”
- Differential mRNA expression in circulating γδ T lymphocyte subsets defines unique tissue‐specific functions (2003, background): “Conversely, cytoskeletal proteins preferentially expressed by CD8 T cells, such as ankyrin, -actinin, adducin, talin, spectrin, and Rho-GTPase-related proteins, might be related to a role in antigen presentation/recognition and in the formation of the “immunological synapse” that would facilitate th”