Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder.

By Christopher S. Monk, Eva H. Telzer, K. Mogg, B. Bradley, Xiaoqin Mai, Hugo M. Louro, Gang Chen, Erin B. McClure-Tone, Monique Ernst, Daniel S. Pine. Archives of General Psychiatry, 2008

680 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/f8fe4148f4eadb62ca52dd758f57f366314d4a03

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In Cognitive Neuroscience

In Experimental and Cognitive Psychology

Citations in the corpus

The Neurocircuitry of Fear, Stress, and Anxiety Disorders (2011, background): “In a study of adolescents with GAD, amygdala responses were positively correlated with GAD symptom severity (Monk et al, 2008).”
Disrupted Amygdalar Subregion Functional Connectivity and Evidence of a Compensatory Network in Generalized Anxiety Disorder (2009, neutral): “By contrast, similar approaches in adolescents with GAD have found hyperactivity in the amygdala.(8,9) Many factors may explain these differences, including differences in baseline amygdalar activity, the caAuthor Affiliations:”
Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond (2017, background): “Specifically, amygdala activation in response to threatening stimuli is increased in PTSD, GAD, social anxiety disorder, specific phobia, and PD (Fonzo et al, 2015; Killgore et al, 2014; Monk et al, 2008).”
Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. (2012, background): “Impaired connectivity between the amygdala and PFC was reported in patients with generalized anxiety disorder (Monk et al., 2008).”
Multiple Arousal Theory and Daily-Life Electrodermal Activity Asymmetry (2016, background): “The amount of right amygdala activation also correlated positively with GAD severity (Monk et al., 2008).”
Reduced resting-state functional connectivity between amygdala and orbitofrontal cortex in social anxiety disorder (2011, background): “…associated with orbitofrontal reactivity during the suppression of negative emotions (Phan et al., 2005) and presence of threatening stimuli (Garcia et al., 1999), in generalized anxiety disorder (Monk et al., 2008) and posttraumatic stress disorder (Shin et al., 2005; Williams et al., 2006).”
How Does Mindfulness Meditation Work? Proposing Mechanisms of Action From a Conceptual and Neural Perspective (2011, neutral): “The relationship between self-compassion and mindfulness In their current conceptualization and operationalization within contemporary research contexts (Baer et al., 2006; Neff, 2003a), mindfulness and self-compassion are highly correlated.”