MDS Task Force on Mild Cognitive Impairment in Parkinson’s disease: Critical Review of PD-MCI
By I. Litvan, Dag Aarsland, C. Adler, J. Goldman, J. Kulisevsky, B. Mollenhauer, M. Rodríguez-Oroz, A. Tröster, Daniel Weintraub. Movement Disorders, 2011
784 citations recorded by the source corpus.
There is controversy regarding the definition and characteristics of mild cognitive impairment in Parkinson's disease. The Movement Disorder Society commissioned a Task Force to critically evaluate the literature and determine the frequency and characteristics of Parkinson's disease–mild cognitive impairment and its association with dementia. A comprehensive PubMed literature review was conducted using systematic inclusion and exclusion criteria. A mean of 26.7% (range, 18.9%–38.2%) of nondemented patients with Parkinson's disease have mild cognitive impairment. The frequency of Parkinson's disease–mild cognitive impairment increases with age, disease duration, and disease severity. Impairments occur in a range of cognitive domains, but single domain impairment is more common than multiple domain impairment, and within single domain impairment, nonamnestic is more common than amnestic impairment. A high proportion of patients with Parkinson's disease–mild cognitive impairment progress to dementia in a relatively short period of time. The primary conclusions of the Task Force are that: (1) Parkinson's disease–mild cognitive impairment is common, (2) there is significant heterogeneity within Parkinson's disease–mild cognitive impairment in the number and types of cognitive domain impairments, (3) Parkinson's disease–mild cognitive impairment appears to place patients at risk of progressing to dementia, and (4) formal diagnostic criteria for Parkinson's disease–mild cognitive impairment are needed. © 2011 Movement Disorder Society
Subfields: Epidemiology, Neurology
View Paper: https://www.semanticscholar.org/paper/f77feedb133e8722ef26ed5c482384495388ff1a
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In Neurology
- Daniel Weintraub
- Ronald C. Petersen
- Michael D. Geschwind
- Michael G. Erkkinen
- Mee‐Ohk Kim
- Dag Aarsland
Citations in the corpus
- Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases. (2018, background): “Cite this article as Cold Spring Harb Perspect Biol doi: 10.1101/cshperspect.a033118 decline in PD is variable early in the disease, with 19%–38% of patients reporting symptoms of mild cognitive impairment in the early stages of PD (Litvan et al. 2011).”
- Diagnostic Criteria for Mild Cognitive Impairment in Parkinson’s Disease: Movement Disorder Society Task Force Guidelines (2012, methodology): “7,8 require (1) a subjective complaint of cognitive decline by the patient, preferably corroborated by a reliable source, (2) minimal effect of the decline on day-to-day functioning and the absence of dementia, and (3) evidence of cognitive abnormalities that cannot be simply attributed to age.”