Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells.

By Siyang Zheng, Henry K. Lin, Jing-Quan Liu, M. Balić, R. Datar, R. Cote, Y. Tai. Journal of Chromatography A, 2007

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Label-free cell separation and sorting in microfluidic systems (2010, background): “5 mL within 10 min and with an efficiency of almost 90% [40].”
Review on Micro- and Nanolithography Techniques and Their Applications (2012, background): “Nowadays, LOC technology has almost reached a level of maturity that promises a variety of applications particularly in fluid manipulation, bio assays and biomolecular analysis.”
A review of microfabrication techniques and dielectrophoretic microdevices for particle manipulation and separation (2014, methodology): “blood cells [29,30] , plasma [31,32], and circulating tumor cells [33]) mechanically based on size has been achieved by fabricating constriction structures (i.”
Circulating tumor cells: approaches to isolation and characterization (2011, neutral): “, 2000) and microelectromechanical systems (Zheng et al., 2007).”