Fundamental studies of a novel, biodegradable PEG-b-PLA hydrogel

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Cell Encapsulation in Biodegradable Hydrogels for Tissue Engineering Applications (2008, positive): “When longer kinetic chains are present, more crosslinks must be broken before the chains are eroded from the gel, which increases overall degradation time and delays reverse gelation.(46,49) The majority of hydrogels engineered to degrade hydrolytically typically hydrolyze via an ester linkage locat”
Review: Photopolymerizable and Degradable Biomaterials for Tissue Engineering Applications (2007, positive): “Metters et al. 53 followed up this study by characterizing the swelling and mechanical behavior of the PEG-b-poly(lactic acid) (PEG-b-PLA) hydrogels with degradation.”
Hydrogels as Extracellular Matrix Mimics for 3D Cell Culture (2009, background): “Synthetic hydrogels have been designed to hydrolytically degrade by incorporating poly(lactic acid) (Metters et al., 2000) or poly(caprolactone) (Nuttelman et al., 2006) units into the network backbone.”